Dr Guy Tsafnat
Senior Research Fellow
I am the head of the
Translational Bioinformatics Group at the Centre for Health Informatics at the University of New South Wales where I lead projects to develop algorithms that use bioinformatics methods and tools for the study of human diseease, and clinical decision support. My background is in computer science, biomedical engineering, and machine learning. Prior to working at CHI I worked for eight years in the software industry in research, development and management roles. My research interests are computer aided discovery, hypothesis generation and testing, ontological knowledge integration, and multi-scale and multi-method model integration as these are applied to translational bioinformatics.
Research Interests
- Molecular biology mechanisms in infectious diseases' resistance to antimicrobial chemotherapies (in collaboration with Westmead Hospital)
- Computer aided discovery in biology and clinical decision support.
- Computational parsing of bioinformatics data.
- Tumour micro-vasculature models - training stochastic 3D models on microscopy datasets for simulating lodgement of micro-spheres for targeted liver cancer treatment planning. (in Collaboration with Uni. of Sydne's Electron Microscope Unit and St. George's Hospital)
- The Field Representation Project is aimed at standardisation of field representations for model interchange, storage and automation.
Past Projects
- Modelling and simulating the Sino-Atrial Node (SAN) as a multi-model of multiple SAN cell models.
- Automatic topic generation in a semi-automated environment (Automatic Topic Generation at Verity Inc.)
- Identification and classification of text documents based on language (Automatic Language Detection at Verity Inc.)
- Host intrusion detection based on abnormal system call execution. (SHIM at NAI Labs)
- I am currently not lecturing but in the past was lecturer in charge of COMP3111 Software Engineering and COMP4001 Object Oriented Software Development in the school of Computer Science and Engineering.
Publications - see the
publications page.
Patents
- Tsafnat G, Ko C and Brutch P Denial of Service (DoS) and Distributed Denial of Service (DDoS) Detection method By Profiling the Kernel's Protocol Stack. for NAI Labs, September 2001