Translational Bioinformatics
The post-genomic era is characterised by the advancement in biotechnology and an exponential growth in biological data. Currently, this technology remains under-utilised because of the inherent complexity of biomedical interactions, and the resulting difficulty in interpreting these data. Transforming genetic and other biological data into useful clinical information has the potential to provide accurate and timely decision support to clinicians, and ultimately deliver optimal and truly evidence-based patient management.
At the Centre for Health Informatics, research is being undertaken to utilise rich and diverse genomic and proteomic data sets to develop next generation clinical decision support. Current research topics include:
- Translating group B streptococcus molecular epidemiology into useful clinical information for infectious disease management and control.
- Transposable element (Mobile Gene Elements) annotation, discovery and catalogging for antibiotics resistance monitoring.
- Antibiotics prescription decision support for clinicians and policy makers.
- Grammatical annotation of DNA assemblies and high-order structures in DNA often consisting of several genes.
CHI's Translational Bioinformatics Group, 5/12/2008